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AI Karyotyping System

AI Karyotyping System

Model: KaryoVision

A deep-learning karyotyping system that automates image selection, chromosome segmentation, pairing and karyogram layout, with over 98% accuracy on haploid identification. It connects to existing microscope imaging systems or automated scanners, so upgrading does not require new hardware.

Specifications

Samples Metaphase spreads from peripheral blood, amniotic fluid, chorionic villi, cord blood and bone marrow
Recognition Deep-learning model, haploid identification accuracy ≥98%
Automated flow Image quality screening → chromosome segmentation → pairing → karyogram layout
Manual tools One-click background removal, overlapping-chromosome splitting, contour editing, band enhancement, centromere adjustment, straightening
Auto calculation Polarity, numbering and centromere position determined automatically; progressive recognition supported
Ideogram Built-in chromosome ideogram editing
Comparison Multi-scenario karyotype comparison, same chromosome across multiple images
Undo Unlimited undo and redo throughout the workflow
Extension Optional FISH image compositing module
Compatibility Works with conventional microscope imaging systems, various cameras and automated slide scanners
Integration Connects to HIS / LIS / PACS; network edition with centralised image capture
Deployment On-premise database, no cloud service required; periodic model updates with self-learning for a local library
Editions Clinical edition / research and teaching edition

Features

  • Over 98% accuracy on haploid identification, taking repetitive pairing and layout work off the operator
  • Full automation from image screening to karyogram layout, cutting turnaround time per case
  • Every conventional manual tool is retained, so automated results can always be corrected by hand
  • Self-learning: corrected cases feed the local model, so accuracy improves with use in the same laboratory
  • On-premise deployment keeps images inside the hospital network
  • Connects to existing microscopes and scanners; no hardware replacement needed to upgrade

Applications

  • Prenatal diagnosis: amniotic fluid, chorionic villi and cord blood karyotyping
  • Peripheral blood lymphocyte chromosome analysis
  • Bone marrow karyotyping in haematological disease
  • Reproductive medicine and genetic counselling
  • Tumour cytogenetics
  • Teaching and research in genetics and cell biology
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